Neuropsychology of Mental Retardation Syndromes
 Welsh, M.C., Pennington, B.F., Ozonoff, S., Rouse, B., &
McCabe, E.R.B. (1990). Neuropsychology of early-treated phenylketonuria:
Specific executive function deficits. Child Development,
61, 1697-1713. Reprinted in Annual Progress in Child Psychiatry and Child
Development, 1991, 24.
Tested the dopamine depletion hypothesis of early-treated PKU by
giving executive function (EF) and recognition memory measures to a preschool
sample and correlating cognitive performance to phenylalanine (Phe) levels.
Found specific EF deficits, which were correlated with Phe levels, thus supporting
the dopamine depletion hypothesis.
Pennington, B.F., Moon, J., Edgin, J., Stedron, J., &
Nadel, L. (2003). The
neuropsychology of Down syndrome: Evidence for hippocampal
dysfunction. Child Development, 74,75-93.
Tested both executive functions and long term memory with multiple measures and
found that the group with Down syndrome were below MA level only on the long term memory measures.
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Other Publication Areas:
Fundamental Issues
Genetics of Dyslexia and Other Learning
Disabilities
Phenotype Analyses of Dyslexia
Neuropsychological Deficits in Autism
Genetics and Neuropsychology of
ADHD
Executive Functions
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