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Knoebel Institute for Healthy Aging

Knoebel Institute

Knoebel Institute for Healthy Aging

Who We Are


Dr. Lotta Granholm-Bentley | Founding Executive Director

Dr. Lotta Granholm-BentleyAnn-Charlotte ("Lotta") Granholm joined the University of Denver on Sept. 1, 2015 as the founding executive director of the Knoebel Institute for Healthy Aging. Granholm is also a research professor in the Department of Biological Sciences at the University of Denver. She comes to DU after 14 years as the director of the Center on Aging at the Medical University of South Carolina. Granholm recently received a three-year appointment as a guest professor in neurosciences at the Karolinska Institute in Stockholm. One of the largest and most prestigious medical universities in the world, Karolinska is the premier research institute in Sweden and the university that gives out the Nobel Prize in Medicine (official name: Nobel Prize in medicine or physiology).

Briony Catlow, Ph.D. | Grant Writer

Briony Catlow PhdBriony joined the Institute in August 2016. She graduated with a bachelor's degree in Biology from the College of Charleston in 2000 and a Ph.D. in Psychology/Neuroscience and a graduate certificate in Aging and Neuroscience from the University of South Florida in 2008. As a graduate student under the tutelage of Cheryl Kirsten Ph.D. and Juan Sanchez-Ramos, M.D. Ph.D. she investigated the effects of psychoactive drugs on neurogenesis and learning and memory. She completed her postdoctoral fellowship in Dr. Ron McKay's laboratory at the National Institute of Neurological Disorders and Stroke (NINDS/NIH) and the Lieber Institute for Brain Development at Johns Hopkins University. Briony then served as the grants administrator at the Lieber Institute where she guided and facilitated faculty and staff in the development and preparation of research proposals, contracts, sub-contracts, and agreements.

Mary B. Cullen | Coordinator

Mary CullenMary B. Cullen joined the Knoebel Institute for Healthy Aging in November 2015. Mary earned a Master of Applied Communication from DU in 2004 and is delighted to return to campus. As the Institute's coordinator, she works with the executive director to create and coordinate the Institute's calendar. Mary also attends construction meetings and coordinates the executive director's move from the Medical University of South Carolina to lab space in the new building. In addition, she works with the Strategic Planning Committee and executive director to develop and refine the vision and mission and strategic plan. Mary also represents the Institute regional aging meetings and is responsible for Institute's communications. Prior to joining DU, Mary was an administrative coordinator for a nonprofit that dealt with improving K-12 education for 10.5 years.

Daniel Paredes, Ph.D. | Assistant Research Professor

Daniel Paredes, Ph.D. Daniel joined the Institute in July 2016. A neurochemist, he previously served as an investigator at the Lieber Institute for Brain Development and an Assistant Professor of Neurology at Johns Hopkins University. As part of his doctoral studies in the Department of Pharmacology and Physiology at the University of South Florida, he demonstrated how the neurochemistry of the aging brain changes while performing a learning and memory task. This study demonstrated that one of the natural occurring mechanisms underlying memory loss in aging is a lack of norepinephrine leading to aberrant memory consolidation. Daniel's interests revolve around understanding the molecular mechanisms of neuronal circuit formation and developing new therapeutic approaches to target neuroplasticity and regeneration in aging and neurodegenerative disorders such as Parkinson's, Alzheimer's and Huntington's Diseases.

Lynn M. Taussig, MD | Special Advisor to the Provost (for Life Sciences)

Dr. Taussig holds the title of Special Advisor to the Provost for Life Sciences at the University of Denver, yet he is much more than that title encompasses; he is a clinician, researcher, educator and entrepreneur. Dr. Taussig was recruited to the University of Denver in 2006 with the task of growing life sciences. He has been instrumental in creating the vision for the implementation of the Knoebel Institute of Healthy Aging and promoting interdisciplinary programs and research focused on Aging. Dr. Taussig continues to help grow the Knoebel Institute for Healthy Aging through strategic planning within DU and collaborations with a number of clinical organizations to support research and education. Dr. Taussig received his undergraduate degree from Harvard University and his medical degree from Washington University School of Medicine. He is a pediatric pulmonologist and former President and CEO of National Jewish Medical and Research Center from which he retired in 2006. He is the author of more than 200 publications, four books, and numerous chapters and monographs related to respiratory illnesses in children and the recipient of numerous honors, including the Alumni Achievement Award from Washington University School of Medicine and the Distinguished Achievement Award from the American Thoracic Society.