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Knoebel Institute for Healthy Aging

Knoebel Institute

Knoebel Institute for Healthy Aging


KIHA captures history from Manhattan project

Dr. H. W. KochOn Monday, January 28, 2019, KIHA filmed Dr. H. William Koch sharing his work on the Manhattan Project. Students of all disciplines will enjoy hearing this lecture on history, physics, World War II and atomic weapons. The Manhattan Project began in 1942 and resulted in production of the atomic bombs that were dropped in August 1945 on Hiroshima and Nagasaki bringing World War II to an end. Dr. Koch's involvement with the Manhattan Project is an intriguing story. He presents a living history of the development of nuclear weapons. Click on this link to watch the story of Dr. Koch's research in physics. 

Dr. Koch originally presented on the evening of December 7, 2018 to a packed event space. He enthralled the audience with his lecture, so we brought him back to present again and recorded his talk. 

KIHA to offer 8-week mindfulness class

Join KIHA for Mindfulness Based Stress Reduction (MBSR), an 8-week course to be held on Tuesdays beginning April 2 through May 21 from 6:00 pm until 8:30pm. There is also an all-day retreat on Saturday, May 11 from 9 am until 4:30 pm. MBSR is an 8-week course designed to cultivate our ability to tap into internal wisdom, wholeness, and healing. Participants will practice mindfulness in a variety of forms, bringing non-judgmental attention to thoughts, feelings, and emotions. The class involves experiential learning and open dialogue around individual experiences. Learn more here. To register, click on this link

former student for KIHA's Concussion study now CLinical resource coordinator

Jenna PowellJenna Powell, a DU alumna who was instrumental in the start of KIHA's concussion study, landed her first post-college job as a clinical research coordinator for Children's Hospital Colorado.Powell double majored in biology and psychology as part of DU's cognitive neuroscience program. During her time at DU, she worked in Dr. Bradley Davidson's Human Dynamics Laboratory. As a senior, Powell was chosen to give a speech at the opening of the Engineering and Computer Science Building. In her current role, Powell hopes to make a difference through orthopedic research in her first job post-graduation. Read more about Powell here

Thank you for celebrating veterans with us in December!

Veteran listening to presentations at Dec. 7th eventWe hope that you had a chance to attend our holiday celebration on December 7. We focused this year's celebration on World War II veterans, and we had some interesting speakers. The first speaker was Dr. William Koch, a 98-year-old physicist who participated in the Manhattan Project as a young graduate student. Everyone so enjoyed his talk that KIHA brought him back on Monday, January 28 to present to the broader community.  

Dr. Leah Weinberg, who is a Visiting Professor in Musicology in the Lamont School, followed Dr. Koch. Dr. Weinberg talked about the history and societal context of the music of the WWII era, including the USO and what that music means to the veterans.

The celebration also featured photographs and stories from U.S. Veterans displayed around the event space for attendees to read about their bravery and life stories. Some photos did not contain a story, a poignant reminder of the ravages of dementia. Dr. Roddy MacInnes, a DU Studio Art and Photography professor, produced these lovely portraits and provided the integrated photo and story prints.

KIHA in the News

University of Denver News

KIHA's Financial Security and Cognitive Health Initiative has attracted attention on campus in late 2018! Dr. Eric Chess received an IMPACT 2025 grant to kickstart this research. This work is featured on the IMPACT 2025 site. Read the IMPACT 2025 update here. And, the University of Denver Magazine reported on the research of Dr. Eric Chess and KIHA's Financial Security and Cognitive Health Initiative. Learn more here.

Want to learn more about KIHA's Concussion Study? View the news story about our Concussion Research Seminar, held on May 30, 2017, here!

Dr Daniel Linseman, a professor in the Department of Biological Sciences and Knoebel Institute for Healthy Aging, leads a team of undergraduate and graduate researchers trying to determine how nutraceuticals — food components used for medicinal purposes — might protect the neurons in the brain that underlie neurodegenerative diseases. The researchers have looked at coffee, green tea, strawberries, blackberries, rosemary, dark chocolate and more in the search for neuroprotective properties. Click here for more details.


The week of September 11, Denver's 9News focused on Alzheimer's disease at the top of the 7 am news hour. 9News invited two KIHA researchers to participate in this week-long feature.

  1. On Monday, September 11, Dr. Granholm-Bentley, executive director of KIHA, discussed her research on Alzheimer's and healthy aging. Watch the clip here
  2. Dr. Eric Chess discussed finances and aging as he wrapped up the week-long discussion. Hear what he had to say. He is the director of KIHA's Financial Security and Cognitive Health Aging Initiative 

Photographs connect people across generations! DU photography professor and KIHA collaborator Roddy MacInnes paired photography students with residents of Clermont Park. Watch the video here for the intergenerational fun had by all. 


Listen to KIHA's latest interview with No Copay Radio! Click below to hear the segment. 

New York Times

Leslie Hasche, Associate Professor in DU's Graduate School of Social Work and member of KIHA's Strategic Planning Group, is quoted in the New York Times. Read the story here.


Previously Funded Pilot Grants


Robin Tinghitella & Shannon Murphy | Biological Sciences | Effects of maternal and grandmaternal aging on offspring health and longevity

Scott Barbee | Biological Sciences | Establishing roles for Vps54 in motor neuron axonal transport and neurodegeneration

Eric Chess | Knoebel Institute for Healthy Aging | Impaired Financial Decision-Making in the Aging Population

Chad Clary | Mechanical and Materials Engineering and Center for Orthopaedic Biomechanics | Pioneering Quantitative Assessments of Disability in the Elderly After Total Knee Replacement Using Wearable Devices and Machine Learning

Bradley Davidson | Mechanical and Materials Engineering | Exosome biomarkers for Traumatic Brain Injury and Alzheimer's Disease

Aurélie Ledreux | Knoebel Institute for Healthy Aging | Brain exosomes as novel biomarkers for Alzheimer's disease: A validation study

Leanne ten Brinke | Psychology | Explaining Older Adults' Truth Bias: A Consequence of Maturational Dualism

Faculty who received pilot grants from the Knoebel Institute in 2017

Eric Boschmann | Geography and the Environment | Mobility Clusters of Older Adults: A National Level Survey Analysis

Elysia Poggi Davis | Psychology | Does prenatal stress impact biological indicators of aging?

Kingshuk Ghosh | Physics and Astronomy and Molecular and Cellular Biophysics | Seeking a molecular mechanism of aging by linking oxidative stress and proteome damage with age

Martin Margittai | Chemistry and Biochemistry | Inhibition of Tau fibril formation

Daniel Paredes | Knoebel Institute for Healthy Aging | Development of a blood biomarker for Parkinson's disease

Kevin Shelburne | Department: Mechanical and Materials Engineering | Improving Function and Satisfaction with Total Shoulder Arthroplasty in the Elderly

Faculty who received pilot grants from the Knoebel Institute in 2016 

Click on the name of the principal investigator to see a video of a previously funded project. 

Drs. Gareth and Sandy Eaton | Chemistry and Biochemistry | Development of a novel imaging method that would allow measurement of oxidative stress (a pathological condition in aging cells) in living cells and eventually in living brain.

Dr. Brian Michel | Chemistry and Biochemistry. Collaboration with Dr. Sean P. Colgan, Dept. of Medicine, CU Anschutz | For discovery of novel drugs to treat kidney associated anemia and improve selectivity and reduce potential side-effects. 

Dr. Daniel Linseman | Biology and KIHA |Collaboration with Dr. Kim Gorgens, Psychology, and Dr. Don Gerber, Craig Hospital | Investigators will test the hypothesis that reduced levels of glutathione (GSH), a major anti-oxidant the body produces, is a principal factor underlying the poorer recovery of older adults from traumatic brain injury (TBI).

Drs. Jennifer Greenfield and Leslie Hasche | GSSW | Understanding the Costs of Caregiving: A Survey of Colorado Caregivers | The proposed pilot study will address a gap in knowledge by testing and administering a survey with caregivers in Colorado, and testing the associations of workplace characteristics with caregiver financial security and well-being.

Dr. Mohammad Mahoor, Engineering. Collaboration with Dr. Adam Hebb, Colorado Neurological Institute. Machine learning algorithms to detect and classify behavior based on analysis of electro-physiological signals from the human brain. The ultimate goal is development of a closed-loop system for deep brain stimulation that would improve therapeutic efficacy in the treatment of Parkinson's disease. Read more here in the University of Denver Magazine.