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Knoebel Institute for Healthy Aging

KIHA Team

Concussion Study

Meet the Team

Faculty Researchers

Dr. Lotta Granholm-Bentley

Lotta

Ann-Charlotte ("Lotta") Granholm joined the University of Denver on Sept. 1, 2015 as the founding executive director of the Knoebel Institute for Healthy Aging. Granholm is also a research professor in the Department of Biological Sciences at the University of Denver. She comes to DU after 14 years as the director of the Center on Aging at the Medical University of South Carolina. Granholm recently received a three-year appointment as a guest professor in neurosciences at the Karolinska Institute in Stockholm. One of the largest and most prestigious medical universities in the world, Karolinska is the premier research institute in Sweden and the university that gives out the Nobel Prize in Medicine (official name: Nobel Prize in medicine or physiology).

BRADLEY DAVIDSON, PH.D.

Brad

Dr. Bradley Davidson is an Assistant Professor in Mechanical Engineering and director of the Human Dynamics Laboratory at the University of Denver and Clinical Assistant Professor at the University of Colorado Anschutz Medical Campus. His research focuses on understanding and characterizing lumbar spine stability in across healthy and pathologic populations through in vivo experimental measurement and musculoskeletal modeling. Specific applications focus on muscle activation and biomechanics of spinal manipulation therapy, geometric modeling of intervertebral kinematics, and muscle coordination and proprioception in the lumbar spine.

 

Dr. Kevin ShelBurne

Kevin

Dr. Shelburne received his bachelors and masters degrees in Mechanical Engineering from Texas A&M University in 1985 and 1988, respectively. He then worked as a Flight Crew Systems Engineer at McDonnell Douglas Space Systems Company, Houston, Texas, where he designed and tested assembly and servicing tasks and robotics systems for the International Space Station. Kevin completed his PhD in Mechanical Engineering at the University of Texas at Austin in May 1997. The focus of his dissertation was the computer modeling and analysis of the normal and reconstructed knee joint. Following his dissertation, Kevin worked for Lockheed Martin Space Systems in the design of new satellite launch vehicles. In 2000, he joined the Biomechanics Research Laboratory at the Steadman-Hawkins Research Foundation, as Assistant Director. In 2002, Kevin was awarded the Journal of Biomechanics Award from the World Congress of Biomechanics. In 2010, Kevin began work as a Senior Research Scientist at the University of Denver, in the department of Mechanical and Materials Engineering. Dr. Shelburne is the author of numerous articles regarding the modeling and simulation of the human musculoskeletal system, and the measurement of joint mechanics using advanced x-ray techniques. He is a current member of the American Society of Mechanical Engineers and Orthopaedic Research Society. Kevin is also Affiliate Faculty at Colorado State University in the department of Veterinary Medicine and Biomedical Sciences. Kevin's hobbies include mountaineering, cycling, photography, skiing, and fishing.

Aurélie Ledreux, Ph.D.

Aurelie

Aurélie Ledreux joined the Institute in October 2016. She graduated with a Bachelor's degree in Biology from the University Pierre et Marie Curie in Paris, France in 2001, and a Ph.D. in Environmental Toxicology from AgroParisTech in Paris, France in 2010. In 2011, she moved from Paris with husband and cat to Charleston, SC when she was awarded with a postdoctoral fellowship from the National Research Council of the National Academies to work at the Marine Biotoxins Program for NOAA. At that time, her research was focused on investigating the transfer of marine biotoxins in the food web. In 2014, she joined Dr. Granholm's lab at the Medical University of South Carolina in Charleston, SC as a postdoctoral researcher to work on the effect of high fat diet and inflammation on cognition and the brain in animal models of aging. Her current research interests focus on healthy aging, and blood biomarkers for neurodegenerative diseases.

KIMBERLY GORGENS, PH.D., ABPP

Kim

Dr. Kim Gorgens is one of the Co-Principal Investigator of the Concussion Biomarker project. She is a Clinical Professor in GSPP and manages a portfolio of other projects that include Traumatic Brain Injury in Criminal Justice research, Financial Decision Making in Older Adults and Antioxidant Therapies for Moderate and Severe TBI's.

 

Daniel Linseman, Ph.D.

Daniel

Daniel Linseman is an associate professor through the Department of Biological Sciences. He received his doctorate in pharmacology from University of Michigan - Ann Arbor and completed his postdoctorate training through Denver Veterans Affairs Medical Center. His primary research interests include how Bcl-2 family proteins regulate mitochondrial oxidative stress.

Daniel Paredes, Ph.D.

Daniel

Daniel joined the Knoebel Institute for Healthy Aging in July 2016. A neurochemist, he previously served as an investigator at the Lieber Institute for Brain Development and an Assistant Professor of Neurology at Johns Hopkins University. As part of his doctoral studies in the Department of Pharmacology and Physiology at the University of South Florida, he demonstrated how the neurochemistry of the aging brain changes while performing a learning and memory task. This study demonstrated that one of the natural occurring mechanisms underlying memory loss in aging is a lack of norepinephrine leading to aberrant memory consolidation. Daniel's interests revolve around understanding the molecular mechanisms of neuronal circuit formation and developing new therapeutic approaches to target neuroplasticity and regeneration in aging and neurodegenerative disorders such as Parkinson's, Alzheimer's and Huntington's Diseases.

Staff Members

Briony Catlow, Ph.D.

Briony

Briony joined the Institute in August 2016. She graduated with a bachelor's degree in Biology from the College of Charleston in 2000 and a Ph.D. in Psychology/Neuroscience and a graduate certificate in Aging and Neuroscience from the University of South Florida in 2008. As a graduate student under the tutelage of Cheryl Kirsten Ph.D. and Juan Sanchez-Ramos, M.D. Ph.D. she investigated the effects of psychoactive drugs on neurogenesis and learning and memory. She completed her postdoctoral fellowship in Dr. Ron McKay's laboratory at the National Institute of Neurological Disorders and Stroke (NINDS/NIH) and the Lieber Institute for Brain Development at Johns Hopkins University. Briony then served as the grants administrator at the Lieber Institute where she guided and facilitated faculty and staff in the development and preparation of research proposals, contracts, sub-contracts, and agreements.

Anah Gilmore

Anah Gilmore joined the team in June 2017, after graduating with honors from Metropolitan State University of Denver with a Bachelor's of Science degree in Biology. Anah discovered her passion for scientific research as an undergraduate intern in Dr. Ravi Mahalingam's lab at the CU Anschutz Medical Campus, where she studied how Simian Varicella Virus (a primate model for the shingles virus) deposited itself in the skin tissue and sweat glands of infected monkeys. Anah earned her National Certification in Phlebotomy and is the staff phlebotomist for the DU's Concussion Study, which aims to research links between biomarkers and repeated concussions. In addition to the concussion project, Anah also manages one of the collaborating centers in the Down Syndrome Brain Consortium, which accepts donations of Down Syndrome brains to further research on the connection between Down Syndrome and Alzheimer's disease. When she isn't in the lab, Anah loves to hike with her husband, Nathan, and rescued Australian Shepherd, Marie.

 Student Researchers

Hannah King, M.A.

HannahHannah King graduated from the Graduate School of Professional Psychology M.A. program in 2018 and now works with CRC as a community member. She received her B.A. from Middlebury College in 2013 and is in the process of applying to doctoral programs to continue her education in clinical psychology. Currently, Hannah works with CRC through records management, data entry, and processing new athlete cohorts.

Hollis Lyman

HollisHollis Lyman is a second year student in the Master of Sport and Performance Psychology at DU. She additionally is a research assistant for Knoebel Institute for Healthy Aging. Her primary responsibilities include assisting in data collection and data entry.

Gabriela Nordeman

GabrielaGabriela Nordeman is a San Francisco native who received her B.S. from the University of California, Davis and M.A. from the University of Denver. She is currently a third-years student in the PsyD program at the University of Denver. She is on the Concussion Biomarker project as a senior research assistant and on the TBI grant as part of the data entry team. She will also be assisting with project and records management on these teams.

 

Nimi Oduleye

NimiNimi has been a Research Coordinator for the Data Entry side of the project since the project's launch in 2016. She is currently a 3rd year PsyD student at Graduate School of Professional Psychology at the University of Denver.

 

 

 

 

 

Moira Pryhoda, M.S.

MoiraMoira Pryhoda is a 3rd year PhD candidate studying biomechanics in the Ritchie School of Engineering and Computer Science. She holds a Bachelor of Science degree in Chemistry (University of Denver) and a Master of Science degree in Geochemistry (Colorado School of Mines). Moira is a researcher in the Concussion Research Collaborative responsible for leading athlete biomechanical balance testing, and processing static and dynamic balance data, with the goal of identifying a clinically feasible biomechanical balance assessment that is sensitive to concussion.

Joey White

JoeyJoey White is a second year student in the Master of Sport and Performance Psychology at the University of Denver's Graduate School of Professional Psychology. He received his B.A. in Biology with a minor in Psychology from the University of Iowa. He is currently a research assistant with the CRC and assists with data collection and data entry.

 

 

Olivia Wyatt

OliviaOlivia Wyatt is in her second year of the Sport & Performance Psychology Master's program at the University of Denver's Graduate School of Professional Psychology. She received her B.S. in Psychology and Economics from Tufts University. Olivia is currently the Program Manager for the CRC. Her work focuses on the qualitative elements of the project, and she assists with data entry.

 

 

Chandler Yunker, M.A.

ChandlerChandler Yunker is a third year student in the PsyD program at the Graduate School of Professional Psychology at the University of Denver. She received her B.A. from Boston University and M.A. from Boston University School of Medicine. Chandler is a student clinician who administers neuropsychological screenings, and is a senior team member on the TBI project. She is also part of the data entry team on the Concussion Biomarker project.