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Development of Non-Enzymatic Glucose Sensors using Copper Electrodes & Nanoparticles

Glucose sensing plays a vital role in various fields, including medical diagnostics, biotechnology, and diabetes management. Traditionally glucose sensing is done using enzymatic sensors, which are susceptible to a variety of changes that can manipulate the effectiveness or reliability of the sensors. Therefore, the increase of demand for developing non-enzymatic sensors that meet or exceed its counterpart. Copper has shown itself to be a suitable and promising material to develop these non-enzymatic sensors. Copper contains this catalytic property when it come into contact with glucose creating a oxidation reduction reaction. Adding in copper nanoparticles can further help improve the sensitivity of the sensors by promoting more of the electrochemical reaction.

The overall objective of this study is to explore and hopefully develop a suitable way of creating these non-enzymatic sensors using Copper nanoparticles and substrate. Investigating the electrochemical performance and comparing the results with other forms of glucose detection. In addition, this study aims to use Copper availability, and “multiple manufacturing techniques” to create a cost-effective sensor that can enhance its feasibility of large-scale production. The study is currently in its first round of iterations for these sensors, testing different variations and individual components to determine the optimal setup that yields the best results in terms of detection limits, sensitivity, and sensor durability.