IRBNet Submission and Post-Approval Monitoring

All research projects that will involve animals must be submitted to the DU IACUC for review and approval.

All IACUC applications must be submitted online through the IRBNet system.

If you have questions and require additional assistance navigating through the IRBNet program, please contact the DU IACUC Office at or call 303-871-2121.

How to Submit on IRBNet

  1. This Process Takes Time! Plan on taking several weeks to gather all your material for submission and then waiting 10 business days for a response on your application.
  2. Register at . Protocols submitted in hard copy or to an e-mail address will not be reviewed.
  3. Create a New Project Refer to How To: Register as a New User & How To: Submit a New IACUC Application)
  4. Upload All Required Documents: application, personal qualifications form, non-surgical procedure, etc.
  5. Share the Project with Research Team
  6. Sign the IRBNet Package
  7. Submit the Package

Post-Approval Monitoring

The IACUC Office conducts annual protocol reviews through a Post Approval Monitoring (PAM) process. This process captures the same information from the previously used Annual Reports more efficiently and without the administrative burden to the investigator. The IACUC Administrator will contact the investigator one month prior to project approval anniversary date to schedule a PAM Meeting. After the meeting, the IACUC Administrator will send the PAM completion report to the investigator for their records and upload a copy into their IRBNet project package. Just like the annual reports, the PAM completion reports are eligible for administrative approval/acknowledgment if there are no significant changes to the protocol. The PAM reports will be reviewed at the IACUC meetings for a follow-up review and acknowledgment.